… T cells also exhibit an activated phenotype but are less efficient in producing cytokines during
chronic … At the same time, intrahepatic levels of γδ T cells were increased [37]. In line with …

… analysis of the T cell phenotype and function during the … , T cell phenotype profiles and
HBV-specific T cell responses … to, during and after achieving functional cure upon treatment and …

… Chronic hepatitis B virus (HBV) infection is characterized by the … CD8 + T cells that hamper
viral control. We investigated the phenotypic heterogeneity of exhausted CD8 + T cells in HBV …

… To analyse the phenotype of virus-specific CD8 + T cells, we investigated the expression …
that chronic hepatitis C creates a profound exhausted signature in HCV-specific CD8 + T cells …

… T-cells, which may display a distinct exhaustion phenotype from intrahepatic T-cells. Since
… characterization of DP T-cells’ phenotype rather than their functional features. Nevertheless, …

… Approximately 60–80% of humans fail to clear the hepatitis C virus infection, and the … ability
of RHV-specific T cells, we stimulated the intrahepatic leukocytes ex vivo using class I and …

… for hepatitis C and D, had HIV infection, autoimmune hepatitis, or … Furthermore, to identify
the functional status of PD- 1+ cells, … Human intrahepatic CD69+ CD8+ T cells have a tissue …

… Furthermore, our study was focused on phenotypical rather than functional markers of
CD8 + T-cell exhaustion and the functional status of these cells remains to be determined. …

… chronic liver infections such as hepatitis B virus (HBV) and hepatitis C virus (HCV) infections,
memory T cells … not definitively demonstrate the phenotype of exhausted T cell at the site of …

… by the hepatitis B (HBV) and hepatitis C (HCV) viruses and the course can be acute or chronic.
… PD-L1 on intrahepatic cells can interact with PD1 on T RM cells, thereby dampening pro-…